Generation of Nonintegrative‐Induced Pluripotent Stem Cells in Hutchinson‐Gilford Progeria Syndrome: Enhancing Aging Research

ABSTRACT Heart failure and cardiovascular disease are the primary causes of mortality in patients with Hutchinson‐Gilford Progeria Syndrome (HGPS), resulting from mutations in the LMNA gene. In this study, we investigated a familial pedigree of HGPS to derive induced pluripotent stem (iPS) cells usi...

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Detalhes bibliográficos

Principais autores:	Juned Kadiwala, Rameen Shakur
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-10-01
coleção:	Aging Medicine
Assuntos:	accelerated aging cardiac markers and disease modeling cardiovascular disease heart failure HGPS iPSC
Acesso em linha:	https://doi.org/10.1002/agm2.70041
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