Generation of Nonintegrative‐Induced Pluripotent Stem Cells in Hutchinson‐Gilford Progeria Syndrome: Enhancing Aging Research

ABSTRACT Heart failure and cardiovascular disease are the primary causes of mortality in patients with Hutchinson‐Gilford Progeria Syndrome (HGPS), resulting from mutations in the LMNA gene. In this study, we investigated a familial pedigree of HGPS to derive induced pluripotent stem (iPS) cells usi...

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Autors principals:	Juned Kadiwala, Rameen Shakur
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-10-01
Col·lecció:	Aging Medicine
Matèries:	accelerated aging cardiac markers and disease modeling cardiovascular disease heart failure HGPS iPSC
Accés en línia:	https://doi.org/10.1002/agm2.70041
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