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With Chitosan and PLGA as the Delivery Vehicle, Toxoplasma gondii Oxidoreductase-Based DNA Vaccines Decrease Parasite Burdens in Mice

Toxoplasma gondii (T. gondii) is an intracellular parasitic protozoan that can cause serious public health problems. However, there is no effectively preventive or therapeutic strategy available for human and animals. In the present study, we developed a DNA vaccine encoding T. gondii oxidoreductase...

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Main Authors: Zhengqing Yu, Wandi Cao, Xuchen Gao, Muhammad Tahir Aleem, Junlong Liu, Jianxun Luo, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
oxidoreductase
chitosan
PLGA
immune protection
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.726615/full
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