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Is CYP-450 enzyme system phenotyping necessary for psychopharmacotherapy of children and adolescents?

Objective: Risperidone is metabolized in liver by CYP2D6 enzyme. Concomitant use of fluoksetine which is an inhibitor of CYP 2D6 with risperidone increases risperidone blood plasma levels by inhibition of 9-hidroxilation of risperidone and other metabolic pathways. Psychotropic drugs are metabolize...

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Autori principali: Birim Sungu Danışmant, Esra Sağlam, Selime Çelik, Ali Fuat Beşkardeş, Nevzat Tarhan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mesut Çetin 2021-03-01
Serie:Psychiatry and Clinical Psychopharmacology
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Accesso online:https://psychiatry-psychopharmacology.com/index.php/pub/article/view/2030
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