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The Role of IL-10 in Malaria: A Double Edged Sword

IL-10 produced by CD4+ T cells suppresses inflammation by inhibiting T cell functions and the upstream activities of antigen presenting cells (APCs). IL-10 was first identified in Th2 cells, but has since been described in IFNγ-producing Tbet+ Th1, FoxP3+ CD4+ regulatory T (Treg) and IL-17-producing...

詳細記述

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書誌詳細
主要な著者: Rajiv Kumar, Susanna Ng, Christian Engwerda
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019-02-01
シリーズ:Frontiers in Immunology
主題:
オンライン・アクセス:https://www.frontiersin.org/article/10.3389/fimmu.2019.00229/full
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