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Anti-Adenoviral Effect of Human Argonaute 2 Alone and in Combination with Artificial microRNAs

During infection, adenoviruses inhibit the cellular RNA interference (RNAi) machinery by saturating the RNA-induced silencing complex (RISC) of the host cells with large amounts of virus-derived microRNAs (mivaRNAs) that bind to the key component of the complex, Argonaute 2 (AGO2). In the present st...

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Autors principals: Philipp Ausserhofer, Izabella Kiss, Angela Witte, Reinhard Klein
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2024-06-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/13/13/1117
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