Synthesis of Unsymmetrical Urea Derivatives via PhI(OAc)₂ and Application in Late-Stage Drug Functionalization

Unsymmetrical urea derivatives are essential structural motifs in a wide array of biologically significant compounds. Despite the well-established methods for synthesizing symmetrical ureas, efficient strategies for the synthesis of unsymmetrical urea derivatives remain limited. In this study, we pr...

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Auteurs principaux:	Subban Kathiravan, Prakriti Dhillon, Tianshu Zhang, Ian A. Nicholls
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2024-11-01
Collection:	Molecules
Sujets:	hypervalent iodine urea amides amines late-stage functionalization drugs
Accès en ligne:	https://www.mdpi.com/1420-3049/29/23/5669
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