Ammonia-triggered disintegration of kappa-carrageenan hydrogel carrier for site-specific anti-inflammatory drug delivery

Ammonia accumulation in tissues is increasingly recognized as a direct biochemical trigger of ammonia-induced inflammation, yet no therapeutic strategy currently exists that can selectively target this pathological condition while minimizing systemic toxicity. Addressing this critical gap, the prese...

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Detalhes bibliográficos

Principais autores:	Sachin Kumar, Priyank Purohit, Surbhi Panwar, Shivsharan Balbhim Kharatmal, Sachin Munjal, Magda H. Abdellattif, Chaitali Anil Thotange, Rachana Sambhaji mane
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
coleção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	ammonia-sensitive hydrogel ammoniasis carrageenan celecoxib dual functional matrix gel disintegration
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbioe.2025.1676330/full
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