Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism

BackgroundParkinson’s disease (PD) is often characterized by altered rates and patterns of neuronal activity in the sensorimotor regions of the basal ganglia thalamocortical network. Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in th...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Noah Hjelle, Biswaranjan Mohanty, Tanner Hubbard, Matthew D. Johnson, Jing Wang, Luke A. Johnson, Jerrold L. Vitek
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-01-01
Schriftenreihe:	Frontiers in Neuroscience
Schlagworte:	Parkinson’s disease rhesus macaque dorsolateral prefrontal cortex go/nogo MPTP
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1521443/full
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