Bacterial cell-free DNA profiling reveals the co-elevation of multiple bacteria in newborn foals with suspected sepsis

Summary: Sepsis is the leading cause of death in neonatal foals, yet current diagnostics lack sufficient sensitivity and specificity. Here, we present a foal cell-free DNA (cfDNA) sequencing for bacterial identification (cfFBI) workflow that integrates wet-lab and computational protocols, enabling d...

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Bibliografische Detailangaben

Hauptverfasser:	Li-Ting Chen, Emmy Wesdorp, Myrthe Jager, Esther W. Siegers, Mathijs J.P. Theelen, Nicolle Besselink, Carlo Vermeulen, Aldert L. Zomer, Els M. Broens, Jaap A. Wagenaar, Jeroen de Ridder
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-12-01
Schriftenreihe:	iScience
Schlagworte:	Equine microbiology Equine pediatric medicine Microbial genomics
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2589004225022667
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