Emerging concepts about NAIP/NLRC4 inflammasomes
NAIP/NLRC4 inflammasome complexes are activated in response to proteins from virulent bacteria that reach the cell cytosol. Specific NAIP proteins bind to the agonists and then physically associate with NLRC4 to form an inflammasome complex able to recruit and activate pro-caspase-1. NAIP5 and NAIP6...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2014-07-01
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| Schriftenreihe: | Frontiers in Immunology |
| Schlagworte: | |
| Online-Zugang: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00309/full |
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