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Emerging concepts about NAIP/NLRC4 inflammasomes

NAIP/NLRC4 inflammasome complexes are activated in response to proteins from virulent bacteria that reach the cell cytosol. Specific NAIP proteins bind to the agonists and then physically associate with NLRC4 to form an inflammasome complex able to recruit and activate pro-caspase-1. NAIP5 and NAIP6...

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Bibliografiske detaljer
Principais autores: Silvia Lucena Lage, Carla eLongo, Laura Migliari Branco, Thais Boccia da Costa, Carina de Lima Buzzo, Karina Ramalho Bortoluci
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014-07-01
Serier:Frontiers in Immunology
Fag:
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00309/full
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