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Emerging concepts about NAIP/NLRC4 inflammasomes

NAIP/NLRC4 inflammasome complexes are activated in response to proteins from virulent bacteria that reach the cell cytosol. Specific NAIP proteins bind to the agonists and then physically associate with NLRC4 to form an inflammasome complex able to recruit and activate pro-caspase-1. NAIP5 and NAIP6...

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Xehetasun bibliografikoak
Egile Nagusiak: Silvia Lucena Lage, Carla eLongo, Laura Migliari Branco, Thais Boccia da Costa, Carina de Lima Buzzo, Karina Ramalho Bortoluci
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2014-07-01
Saila:Frontiers in Immunology
Gaiak:
Sarrera elektronikoa:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00309/full
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