Antipathogenic Compounds That Are Effective at Very Low Concentrations and Have Both Antibiofilm and Antivirulence Effects against Pseudomonas aeruginosa

ABSTRACT Pseudomonas aeruginosa, a human pathogen, causes both acute and chronic infections that are mediated by virulence factor production and biofilm formation. Since both characteristics of P. aeruginosa are regulated by quorum sensing (QS), we screened 126 synthetic chemicals for anti-QS activi...

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Detalhes bibliográficos

Principais autores:	Hyeon-Ji Hwang, Heejeong Choi, Sojeong Hong, Hyung Ryong Moon, Joon-Hee Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2021-10-01
Colecção:	Microbiology Spectrum
Assuntos:	Pseudomonas aeruginosa quorum sensing biofilm virulence antivirulence antibiofilm
Acesso em linha:	https://journals.asm.org/doi/10.1128/Spectrum.00249-21
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