Dexmedetomidine vs. propofol for sedation in mechanically ventilated ICU patients: a systematic review and meta-analysis of randomized controlled trials

BackgroundDexmedetomidine and propofol are the two most widely used non-benzodiazepine sedatives for mechanically ventilated ICU patients. Despite guideline recommendations for both agents, the optimal choice remains controversial owing to inconsistent evidence across patient subpopulations.MethodsW...

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Главные авторы:	Xiao-Yan Zhang, Song Qin, Meng-Jun Liu, Yun-Yan Wang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2026-07-01
Серии:	Frontiers in Neurology
Предметы:	bradycardia delirium dexmedetomidine ICU sedation mechanical ventilation meta-analysis
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fneur.2026.1875240/full
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