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An integrated population pharmacokinetic model of febuxostat in pediatric patients with hyperuricemia including gout and adult population of healthy subjects and patients with renal dysfunction

Abstract The study objective was to validate febuxostat dosage and administration in pediatric patients with hyperuricemia including gout, using an integrated population pharmacokinetic (PopPK) analysis in the Japanese population. Integrated PopPK analysis of febuxostat used a nonlinear mixed‐effect...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Ryutaro Iwama, Kimie Nishida, Daisuke Ishii, Takeshi Iijima
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Wiley 2024-12-01
Цуврал:Pharmacology Research & Perspectives
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1002/prp2.70032
Шошгууд: Шошго нэмэх
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