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Regulation of p53 by jagged1 contributes to angiotensin II-induced impairment of myocardial angiogenesis.

Angiotensin II (AngII) is a major contributor to the development of heart failure, however, the molecular and cellular mechanisms still remain elucidative. Inadequate angiogenesis in myocardium leads to transition from cardiac hypertrophy to dysfunction, this study was therefore conducted to examine...

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Detalhes bibliográficos
Principais autores: Aili Guan, Hui Gong, Yong Ye, Jianguo Jia, Guoping Zhang, Bingyu Li, Chunjie Yang, Sanli Qian, Aijun Sun, Ruizhen Chen, Junbo Ge, Yunzeng Zou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3789680?pdf=render
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