SHORTER trial: protocol for a pragmatic, multicentre, randomised controlled trial of short-duration antibiotic therapy for critically ill patients with sepsis

Introduction Sepsis is a life-threatening syndrome resulting from a dysregulated immune response to an infection. Patients with sepsis can become critically ill and require advanced organ support in a hospital critical care setting. Antibiotics are lifesaving in sepsis, but overuse is associated wit...

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Автори:	A John Simpson, Daniel Francis McAuley, Helen Mossop, Paul Dark, Anthony C Gordon, Laura Ternent, Margaret Ogden, Jamie Smith, Tim Felton, Miranda Morton, Rashmi Kumar, Timothy Walsh, Helen C Hancock, Lydia M Emerson, Cristina Fernandez-Garcia, Ronan McMullan, Thomas P Hellyer, Phil Mawson, Anthony Rostron, Hangjian Wu, Sarah Al-Ashmori, Rebecca Wafer, Zoe Walmsley, Gosha Colquhoun, Laura Loraine, Leia Taylor, Sipho Ndlovu, Phil Hall
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMJ Publishing Group 2026-03-01
Серія:	BMJ Open
Онлайн доступ:	https://bmjopen.bmj.com/content/16/3/e117142.full
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