L-Phenylalanine promotes liver steatosis by inhibiting BNIP3-mediated mitophagy

Abstract Background L-Phenylalanine (L-Phe) levels are elevated in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). However, whether L-Phe induces liver steatosis and the underlying mechanism remain unknown. This study aimed to investigate the mechanism through which L...

Descripción completa

Detalles Bibliográficos

Autores principales:	Ying Sun, Lingli Cai, Bowei Yu, Haojie Zhang, Ziteng Zhang, Xiaoqin Xu, Yuefeng Yu, Jiang Li, Chi Chen, Fangzhen Xia, Yingli Lu, Kun Zhang, Ningjian Wang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-06-01
Colección:	Molecular Medicine
Materias:	Liver steatosis L-Phenylalanine Mitophagy BNIP3
Acceso en línea:	https://doi.org/10.1186/s10020-025-01303-5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!