Evaluation of Pulsed Current Iontophoresis for Enhancing the Transdermal Absorption of the Osteoporosis Drug Teriparatide

This study aimed to evaluate the feasibility and safety of pulsed-current iontophoresis (IP) for the transdermal delivery of teriparatide, a therapeutic peptide for osteoporosis. Female rats were subjected to in vivo iontophoretic administration under constant or pulsed-current conditions. Serum ter...

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Detalhes bibliográficos

Principais autores:	Ryuse Sakurai, Haruka Takenaka, Hiroyuki Ogino, Takashi Ishiyama, Issei Takeuchi, Akiyoshi Saitoh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-01-01
coleção:	Colloids and Interfaces
Assuntos:	macromolecular drugs treatment of osteoporosis blood drug concentration transepidermal water loss (TEWL) skin irritation assessment pulsed iontophoresis
Acesso em linha:	https://www.mdpi.com/2504-5377/10/1/15
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