REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells

Ischemic-reperfusion injury (IRI) is a major pathogenic factor in acute kidney injury (AKI), which directly leads to the hypoxic injury of renal tubular epithelial cells (RTECs). Although emerging studies suggest repressor element 1–silencing transcription factor (REST) as a master regulator of gene...

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Detalhes bibliográficos

Principais autores:	Shuiqin Gong, Aihong Zhang, Mengying Yao, Wang Xin, Xu Guan, Shaozong Qin, Yong Liu, Jiachuan Xiong, Ke Yang, Li Xiong, Ting He, Yinghui Huang, Jinghong Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical investigation 2023-06-01
coleção:	JCI Insight
Assuntos:	Nephrology
Acesso em linha:	https://doi.org/10.1172/jci.insight.166001
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