SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12

Summary: Mitochondrial DNA (mtDNA) encodes thirteen core components of OXPHOS complexes, and its steady expression is crucial for cellular energy homeostasis. However, the regulation of mtDNA expression machinery, along with its sensing mechanism to energetic stresses, is not fully understood. Here,...

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Detalhes bibliográficos

Principais autores:	Yuan Ma, Suwei Zhu, Tingting Lv, Xia Gu, Hong Feng, Junhui Zhen, Wei Xin, Qiang Wan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-08-01
Colecção:	iScience
Assuntos:	Biological Sciences Cell Biology Functional Aspects of Cell Biology Molecular Biology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004220306180
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