CD80+ Macrophage-Induced IL-17+CD8+ T cells accumulate in hyperlipidemic patients and murine vascular lesions to promote atherosclerotic progression

Abstract Background Tc17 cells (IL-17 + CD8+T) are found in many inflammatory diseases. However, the distribution, regulation, and function of Tc17 cells in ApoE deficient-induced atherosclerosis are currently largely unexplored. Methods The percentage of Tc17 cells, monocytes and IL-1β+ monocytes i...

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Autori principali:	Yin Wang, Pan Li, Wenming Li, Yao Zou, Ying Zhao, Limei Ma, Tingrui Zhao, Xinyu Chai, Siyi Liu, Zhiyi Yuan, Moustapha Hassan, Tingting Wang, Chao Yu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-03-01
Serie:	Cell Communication and Signaling
Soggetti:	Atherosclerosis Tc17 cells CD80+ monocytes/macrophages IL-1β
Accesso online:	https://doi.org/10.1186/s12964-026-02785-4
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