A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

To become and remain functional, individual neuron types must select during development and maintain throughout life their distinct terminal identity features, such as expression of specific neurotransmitter receptors, ion channels and neuropeptides. Here, we report a molecular mechanism that enable...

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Hlavní autoři:	Weidong Feng, Yinan Li, Pauline Dao, Jihad Aburas, Priota Islam, Benayahu Elbaz, Anna Kolarzyk, André EX Brown, Paschalis Kratsios
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2020-01-01
Edice:	eLife
Témata:	neuronal identity transcription factors Hox proteins terminal selectors UNC-3/Collier/Ebf
On-line přístup:	https://elifesciences.org/articles/50065
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