Pseudo-Prolines: Reversible Conformational Trap of Cyclosporin C as Novel Concept for Prodrug Design
The selective and reversible insertion of pseudo-proline (? Pro) systems in cyclosporin C (CsC) featuring different C(2) substituents at the oxazolidine ring and its impact on the conformational and biological properties is described. The presence of a 5-membered ring exerts drastic effect...
Gardado en:
| Principais autores: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Alemão |
| Publicado: |
Swiss Chemical Society
2004-04-01
|
| Series: | CHIMIA |
| Assuntos: | |
| Acceso en liña: | https://chimia.ch/chimia/article/view/3841 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|