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Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity

Abstract Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF‐α display pro‐inflammatory actions on endothelial cells and atherosclerotic plaques....

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Asıl Yazarlar: Silvia Oggero, Monica deGaetano, Simone Marcone, Stephen Fitzsimons, Andreia L. Pinto, Dinara Ikramova, Mary Barry, David Burke, Trinidad Montero‐Melendez, Dianne Cooper, Thomas Burgoyne, Orina Belton, Lucy V. Norling, Eoin P. Brennan, Catherine Godson, Mauro Perretti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2021-04-01
Seri Bilgileri:Journal of Extracellular Vesicles
Konular:
extracellular vesicles
monocyte/platelet aggregates
proteomics
vascular inflammation
Online Erişim:https://doi.org/10.1002/jev2.12084
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