Posterior enhancer (p-Enh) maintains early neuromesodermal progenitors bi-potency during gastrulation

Abstract Vertebrate axis patterning requires precise control of the differentiation of neuromesodermal progenitors (NMPs), which generate spinal cord (SC) and presomitic mesoderm (PSM). Previously, we identified a gastrula-premarked posterior enhancer (p-Enh) that is essential for posterior tissue d...

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Huvudupphov:	Panpan Mi, Yingying Chen, Fengxiang Tan, Penglei Shen, Yun Yang, Mingzhu Wen, Yun Qian, Jichang Wang, Naihe Jing, Xianfa Yang
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	SpringerOpen 2025-11-01
Serie:	Cell Regeneration
Ämnen:	Gastrulation Neuromesodermal progenitors Enhancer Cell fate determination ST-Pheno
Länkar:	https://doi.org/10.1186/s13619-025-00272-8
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