Sensing HIV Protease and Its Inhibitor Using “Helical Epitope”—Imprinted Polymers

A helical epitope-peptide (lle⁸⁵-Gly⁹⁴) was selected from the α-helix structure of the HIV protease (PR) as the template, which represents an intricate interplay between structure conformation and dimerization. The peptide template was mixed with water, trifluoroethanol (TFE),...

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Autors principals:	Chien-Yu Chou, Chung-Yin Lin, Cheng-Hsin Wu, Dar-Fu Tai
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-06-01
Col·lecció:	Sensors
Matèries:	molecularly imprinted polymers quartz crystal microbalance HIV protease protease inhibitor nelfinavir helical epitope
Accés en línia:	https://www.mdpi.com/1424-8220/20/12/3592
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