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Shikonin Inhibits APC-mutant Colon Cancer via Wnt/β-catenin Signaling

Objective To identify small molecule inhibitors of APC-mutant colon cancer and provide lead compounds for targeted therapy of colon cancer. MethodsAPC-mutant colon cancer cell lines that stably express 7*Tcf-GFP/SV40-Cherry (7TGC) dual fluorescence reporter system was constructed for small-molecule...

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Principais autores: Lizhe CHEN, Bojun WANG, Qing GONG, Xue ZHANG, Xisong KE
Formato: Artigo
Idioma:Chinês
Publicado em: Magazine House of Cancer Research on Prevention and Treatment 2024-06-01
coleção:Zhongliu Fangzhi Yanjiu
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Acesso em linha:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2024.24.0121
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