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SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro

SARS-CoV-2 infection can cause fatal inflammatory lung pathology, including thrombosis and increased pulmonary vascular permeability leading to edema and hemorrhage. In addition to the lung, cytokine storm-induced inflammatory cascade also affects other organs. SARS-CoV-2 infection-related vascular...

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Principais autores: Fengming Liu, Kun Han, Robert Blair, Kornelia Kenst, Zhongnan Qin, Berin Upcin, Philipp Wörsdörfer, Cecily C. Midkiff, Joseph Mudd, Elizaveta Belyaeva, Nicholas S. Milligan, Tyler D. Rorison, Nicole Wagner, Jochen Bodem, Lars Dölken, Bertal H. Aktas, Richard S. Vander Heide, Xiao-Ming Yin, Jay K. Kolls, Chad J. Roy, Jay Rappaport, Süleyman Ergün, Xuebin Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-07-01
coleção:Frontiers in Cellular and Infection Microbiology
Assuntos:
endothelial cell infection
animal models
SARS-CoV-2
aorta ring
hACE2
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcimb.2021.701278/full
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