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Time-dependent histological characterization of amyloid-β induced cholinergic and glial alterations and their modulation by dehydroepiandrosterone sulfate (DHEAS)

IntroductionAlzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by predominant - but not exclusive - pathological accumulation of amyloid-β (Aβ) in the brain. This process affects not only neurons (particularly cholinergic) but also glial cells, contributing to prog...

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Hauptverfasser: Csenge Sólyomvári, Géza Makkai, Nicolas Capelo-Carrasco, Dubravka Svob Strac, Dóra Zelena, Szidónia Farkas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-03-01
Schriftenreihe:Frontiers in Endocrinology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fendo.2026.1764298/full
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