Preferential Reactivity of Dipeptidyl Peptidase-IV Inhibitor-Associated Bullous Pemphigoid Autoantibodies to the Processed Extracellular Domains of BP180

Bullous pemphigoid (BP) is a common autoimmune blistering disease in which autoantibodies target the hemidesmosomal components BP180 and/or BP230 in basal keratinocytes. In BP, 80 to 90% of autoantibodies target the juxtamembranous extracellular non-collagenous 16th A (NC16A) domain of BP180. Recent...

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Autori principali:	Yosuke Mai, Wataru Nishie, Kentaro Izumi, Hiroshi Shimizu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2019-05-01
Serie:	Frontiers in Immunology
Soggetti:	bullous pemphigoid dipeptidyl peptidase-IV inhibitor dipeptidyl peptidase-IV inhibitor-associated bullous pemphigoid autoantibodies IgG subclass BP180
Accesso online:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01224/full
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