Quantifying the utility of type 2 diabetes polygenic risk score for predicting incident diabetes: an analysis of large US-based cohort studies

Abstract Background Genome-wide association analyses (GWASs) have identified numerous genetic variants associated with type 2 diabetes, but the utility of polygenic risk scores (PRSs) derived from these associations for predicting future incident diabetes remains uncertain. We analyzed utility of PR...

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Detalhes bibliográficos

Principais autores:	Robert L Hanson, Sayuko Kobes, Lauren E Wedekind, Elsa Vazquez Arreola, Maria Jose Ramirez-Luzuriaga, Wen-Chi Hsueh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-05-01
coleção:	BMC Medical Genomics
Assuntos:	Type 2 diabetes Prediction Polygenic risk score
Acesso em linha:	https://doi.org/10.1186/s12920-026-02386-7
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