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Matrix Stiffness Affects Glycocalyx Expression in Cultured Endothelial Cells

Rationale: The endothelial cell glycocalyx (GCX) is a mechanosensor that plays a key role in protecting against vascular diseases. We have previously shown that age/disease mediated matrix stiffness inhibits the glycocalyx glycosaminoglycan heparan sulfate and its core protein Glypican 1 in human um...

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Autors principals: Marwa Mahmoud, Limary Cancel, John M. Tarbell
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-10-01
Col·lecció:Frontiers in Cell and Developmental Biology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fcell.2021.731666/full
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