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Local intra-articular injection of rapamycin inhibits NLRP3 activity and prevents osteoarthritis in mouse DMM models

This study investigated the influence of autophagy on the expression of Collagen type II and light chain 3 (LC-3) in the articular cartilage of osteoarthritis (OA) models. The expression of OA associated biomarkers namely Matrix metalloproteinase (MMP-13), NOD-, LRR- and pyrin domain-containing 3 (N...

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Detalles Bibliográficos
Principais autores: Gang Xu, Jian Wang, Long Ma, Xin Zhao, Wen Luo, Qunhua Jin
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2019-05-01
Series:Autoimmunity
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Acceso en liña:http://dx.doi.org/10.1080/08916934.2019.1643844
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