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Significance of anti-neutrophil cytoplasmic antibodies in systemic sclerosis

Abstract Background Up to 12% of patients with systemic sclerosis (SSc) have anti-neutrophil cytoplasmic antibodies (ANCA). However, the majority of these patients do not manifest ANCA-associated vasculitis (AAV) and the significance of ANCA in these patients is unclear. The aim of this study is to...

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Principais autores: Jayne Moxey, Molla Huq, Susanna Proudman, Joanne Sahhar, Gene-Siew Ngian, Jenny Walker, Gemma Strickland, Michelle Wilson, Laura Ross, Gabor Major, Janet Roddy, Wendy Stevens, Mandana Nikpour
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-02-01
coleção:Arthritis Research & Therapy
Assuntos:
Anti-neutrophil cytoplasmic antibodies (ANCA)
Systemic sclerosis (SSc)
ANCA-associated vasculitis
Myeloperoxidase (MPO)
Proteinase-3 (PR3)
Acesso em linha:http://link.springer.com/article/10.1186/s13075-019-1839-5
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