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Analysis of eligibility criteria in Alzheimer’s and related dementias clinical trials

Abstract Overly restrictive clinical trial eligibility criteria can reduce generalizability, slow enrollment, and disproportionately exclude historically underrepresented populations. The eligibility criteria for 196 Alzheimer’s Disease and Related Dementias (AD/ADRD) trials funded by the National I...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Alexandra K. Mitchell, Rebecca Ehrenkranz, Sanne Franzen, Sae H. Han, Mujaahida Shakur, Melissa McGowan, Holly A. Massett
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-07-01
Schriftenreihe:Scientific Reports
Schlagworte:
Alzheimer disease
Dementia
Eligibility criteria
Patient selection
Clinical trials
Diversity
Online-Zugang:https://doi.org/10.1038/s41598-024-65767-x
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