CD11b Signaling Prevents Chondrocyte Mineralization and Attenuates the Severity of Osteoarthritis

Osteoarthritis (OA) is a progressive joint disease that is strongly associated with calcium-containing crystal formation (mineralization) by chondrocytes leading ultimately to cartilage calcification. However, this calcification process is poorly understood and treatments targeting the underlying di...

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Hlavní autoři:	Driss Ehirchiou, Ilaria Bernabei, Véronique Chobaz, Mariela Castelblanco, Thomas Hügle, Alexander So, Li Zhang, Nathalie Busso, Sonia Nasi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-12-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	CD11b integrin calcium-containing crystals osteoarthritis animal model chondrocyte mineralization
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2020.611757/full
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