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The CDK-activating kinase (CAK) Csk1 is required for normal levels of homologous recombination and resistance to DNA damage in fission yeast.

BACKGROUND: Cyclin-dependent kinases (CDKs) perform essential roles in cell division and gene expression in all eukaryotes. The requirement for an upstream CDK-activating kinase (CAK) is also universally conserved, but the fission yeast Schizosaccharomyces pombe appears to be unique in having two CA...

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Bibliografske podrobnosti
Principais autores: Hilary B Gerber, Yana Pikman, Robert P Fisher
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2008-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC2200797?pdf=render
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