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Simultaneous cyclin D1 overexpression and p27kip1 knockdown enable robust Müller glia cell cycle reactivation in uninjured mouse retina

Harnessing the regenerative potential of endogenous stem cells to restore lost neurons is a promising strategy for treating neurodegenerative disorders. Müller glia (MG), the primary glial cell type in the retina, exhibit extraordinary regenerative abilities in zebrafish, proliferating and different...

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Bibliografske podrobnosti
Principais autores: Zhifei Wu, Baoshan Liao, Julia Ying, Jan Keung, Zongli Zheng, Virpi Ahola, Wenjun Xiong
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications Ltd 2025-04-01
Serija:eLife
Teme:
Online dostop:https://elifesciences.org/articles/100904
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