Can radiosensitivity associated with defects in DNA repair be overcome by mitochondrial-targeted antioxidant radioprotectors

Radiation oncologists have observed variation in normal tissue responses between patients in many instances with no apparent explanation. The association of clinical tissue radiosensitivity with specific genetic repair defects (Wegner’s Syndrome, Ataxia Telangiectasia, Bloom’s Syndrome, and Fanconi...

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Detalhes bibliográficos

Principais autores:	Joel S Greenberger, Hebist eBerhane, Ashwin eShinde, Byung Han Rhieu, Mark eBernard, Peter eWipf, Erin M. Skoda, Michael Wayne Epperly
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-02-01
coleção:	Frontiers in Oncology
Assuntos:	Fanconi Anemia Mitochondria Radioprotectors GS-Nitroxide Clinical Radiosensitivity
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00024/full
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