Detailed modeling of positive selection improves detection of cancer driver genes
Finding driver genes sheds lights on the biological mechanisms propelling the development of a tumour, and can suggest therapeutic strategies. Here, the authors develop driverMAPS, a model-based approach to identify driver genes, and apply it to TCGA datasets.
Guardat en:
| Autors principals: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2019-07-01
|
| Col·lecció: | Nature Communications |
| Accés en línia: | https://doi.org/10.1038/s41467-019-11284-9 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|