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Dexmedetomidine preconditioning inhibits the long term inflammation induced by renal ischemia/reperfusion injury in rats

PURPOSE: To investigate the protective effects of dexmedetomidine (Dex) against renal ischemia/reperfusion injury (IRI). METHODS: Sprague-Dawley rats were randomly divided to sham group, IRI group and Dex group. The SD rats were subjected to 45 min of ischemia followed by eight weeks of reperfusi...

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Huvudupphov: Guiyong Liu, Hongfei Song, Lili Qiu, Anren He, Fangfang Tong, Qifu Wan, Xin Wang, Yunfang Xia, Lequn Huang
Materialtyp: Artigo
Språk:Inglês
Utgiven: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2016-01-01
Serie:Acta Cirúrgica Brasileira
Ämnen:
Dexmedetomidine
Ischemia
Reperfusion Injury
Inflammation
Rats
Länkar:http://www.scielo.br/pdf/acb/v31n1/0102-8650-acb-31-01-00008.pdf
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