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Identification of Chagas disease biomarkers using untargeted metabolomics

Abstract Untargeted metabolomic analysis is a powerful tool used for the discovery of novel biomarkers. Chagas disease (CD), caused by Trypanosoma cruzi, is a neglected tropical disease that affects 6–7 million people with approximately 30% developing cardiac manifestations. The most significant cli...

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Autori principali: Alfonso Herreros-Cabello, Pau Bosch-Nicolau, José A. Pérez-Molina, Fernando Salvador, Begoña Monge-Maillo, Jose F. Rodriguez-Palomares, Antonio Luiz Pinho Ribeiro, Adrián Sánchez-Montalvá, Ester Cerdeira Sabino, Francesca F. Norman, Manuel Fresno, Núria Gironès, Israel Molina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-08-01
Serie:Scientific Reports
Soggetti:
Chagas disease
Untargeted metabolomics
Biomarkers
Chronic chagasic cardiomyopathy
Accesso online:https://doi.org/10.1038/s41598-024-69205-w
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