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Validation of deuterium incorporation against sterol balance for measurement of human cholesterol biosynthesis

To examine the validity of the deuterium (D) incorporation technique for measurement of human cholesterol synthesis rates, D uptake from D2O into cholesterol was compared to sterol balance in 13 subjects each under three controlled diet settings. Subjects (age 62 ± 3.6 yr, body weight 74 ± 4.0 kg, B...

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Main Authors: P.J.H. Jones, L.M. Ausman, D.H. Croll, J.Y. Feng, E.A. Schaefer, A.H. Lichtenstein
Format: Artigo
Language:Inglês
Published: Elsevier 1998-05-01
Series:Journal of Lipid Research
Subjects:
cholesterol
biosynthesis
deuterium
sterol balance
diet fat
human
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338815
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