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Cholesterol Alters the Phase Separation in Model Membranes Containing hBest1

Human retinal pigment epithelial (RPE) cells express the transmembrane Ca<sup>2+</sup>-dependent Cl<sup>−</sup> channel bestrophin-1 (hBest1) of the plasma membrane. Mutations in the hBest1 protein are associated with the development of distinct pathological conditions known as bestrophinopathies. T...

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Principais autores: Pavel Videv, Kirilka Mladenova, Tonya D. Andreeva, Jong Hun Park, Veselina Moskova-Doumanova, Svetla D. Petrova, Jordan A. Doumanov
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-07-01
Serier:Molecules
Fag:
hBest1
cholesterol
POPC
SM
phase separation
Online adgang:https://www.mdpi.com/1420-3049/27/13/4267
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