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m5C RNA modification in gastrointestinal cancers: a comprehensive review from molecular mechanism to clinical implication

Abstract 5-methylcytosine (m5C) modification has emerged as a novel epigenetic modification of ribonucleic acids (RNAs), encompassing messenger RNAs (mRNAs) and non- coding RNAs, in recent years. This reversible modification, which is regulated by m5C regulators consisting of methyltransferases, dem...

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Principais autores: Chao Xu, Qinwen Ye, Hao Wang, Yue Yu
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2026-04-01
סדרה:Biology Direct
נושאים:
Epigenetics
Cancer
5-methylcytosine
m5C
RNA modifications
RNA metabolism
גישה מקוונת:https://doi.org/10.1186/s13062-026-00792-6
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