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A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs

Comparison of observed exon–exon junction counts to those predicted from estimated transcript abundances can identify genes with misannotated or misquantified transcripts. Most methods for statistical analysis of RNA-seq data take a matrix of abundance estimates for some type of genomic features as...

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Bibliografiset tiedot
Päätekijät: Charlotte Soneson, Michael I Love, Rob Patro, Shobbir Hussain, Dheeraj Malhotra, Mark D Robinson
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Life Science Alliance LLC 2019-02-01
Sarja:Life Science Alliance
Linkit:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201800175
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