Dynamics of CLIMP-63 S-acylation control ER morphology
A key player in the formation of endoplasmic reticulum sheets is CLIMP-63, but mechanistic details remained elusive. Here authors combined cellular experiments and mathematical modelling to show that S-acylation of CLIMP-63 regulates its function by mediating its oligomerisation, turnover, and local...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2023-01-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-023-35921-6 |
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