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Systematic evaluation of markers used for the identification of human induced pluripotent stem cells

Low efficiency of somatic cell reprogramming and heterogeneity among human induced pluripotent stem cells (hiPSCs) demand extensive characterization of isolated clones before their use in downstream applications. By monitoring human fibroblasts undergoing reprogramming for their morphological change...

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Principais autores: Sumitha Prameela Bharathan, Kannan Vrindavan Manian, Syed Mohammed Musheer Aalam, Dhavapriya Palani, Prashant Ajit Deshpande, Mankuzhy Damodaran Pratheesh, Alok Srivastava, Shaji Ramachandran Velayudhan
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2017-01-01
Series:Biology Open
Assuntos:
Reprogramming
Human induced pluripotent stem cells
Retroviral silencing
hiPSC morphology
Colony identification
Pluripotency
Acceso en liña:http://bio.biologists.org/content/6/1/100
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