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Layered and integrated medical countermeasures against Burkholderia pseudomallei infections in C57BL/6 mice

Burkholderia pseudomallei, the gram-negative bacterium that causes melioidosis, is notoriously difficult to treat with antibiotics. A significant effort has focused on identifying protective vaccine strategies to prevent melioidosis. However, when used as individual medical countermeasures both anti...

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Autori principali: Christopher P. Klimko, Jennifer L. Shoe, Nathaniel O. Rill, Melissa Hunter, Jennifer L. Dankmeyer, Yuli Talyansky, Lindsey K. Schmidt, Caitlyn E. Orne, David P. Fetterer, Sergei S. Biryukov, Mary N. Burtnick, Paul J. Brett, David DeShazer, Christopher K. Cote
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-08-01
Serie:Frontiers in Microbiology
Soggetti:
Burkholderia pseudomallei
melioidosis
vaccine
antibiotics
mice
aerosols
Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2022.965572/full
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